张玲玲 教授 博士生导师

邮箱：lingling80@ouc.edu.cn  

电话：0532-82031969  

地址：青岛市鱼山路5号中国海洋大学化学馆220

学习工作简历

1998-2002年，中国海洋大学，学士

2002-2007年，中国海洋大学，博士

2007-2010年，美国德克萨斯大学奥斯汀分校，博士后

2011年至今，中国海洋大学海洋生命学院，教师

研究方向

主要从事贝类分子遗传学。针对海洋贝类多样化的生殖方式，利用基因组学、转录组学、表观组等前沿技术方法，解析海洋贝类性别决定分化及性腺发育的分子机制，探索实现贝类生殖调控的途径。

代表性文章（#共同第一；*通讯作者）

Zhang M^#, Wei H^#, Liu T, Li W, Li Y, Wang S, Xing Q, Hu X, Zhang L*, Bao Z. (2020). Potential GnRH and steroidogenesis pathways in the scallop Patinopecten yessoensis. Journal of Steroid Biochemistry and Molecular Biology. 204:105756.

Wang J^#, Zhang L^#, Lian S^#, Qin Z^#, Zhu X^#, Dai X, Huang Z, Ke C, Zhou Z, Wei J, Liu P, Hu N, Zeng Q, Dong B, Dong Y, Kong D, Zhang Z, Liu S, Xia Y, Li Y, Zhao L, Xing Q, Huang X, Hu X, Bao Z & Wang S*. (2020) Evolutionary transcriptomics of metazoan biphasic life cycle supports a single intercalation origin of metazoan larvae. Nature Ecology & Evolution. 4(5):725-736.

Li Y^#, Zhang L^#,*, Li R, Zhang M, Li Y, Wang H, Wang S, Bao Z. (2019) Systematic identification and validation of the reference genes from 60 RNA-Seq libraries in the scallop Mizuhopecten yessoensis. BMC Genomics. 20:288.

Xing Q^#, Zhang L^#, Li Y, Zhu X, Li Y, Guo H, Bao Z, Wang S*. (2019) Development of novel cardiac indices and assessment of factors affecting cardiac activity in a bivalve mollusc Chlamys farreri. Frontiers in Physiology. 10:293.

Li Y^#, Zhang L^#, Li Y, Li W, Guo Z, Li R, Hu X, Bao Z, Wang S*. (2019) Dynamics of DNA methylation and DNMT expression during gametogenesis and early development of scallop Patinopecten yessoensis. Marine Biotechnology. 21:196-205.

Li R^#, Zhang L^#,*, Li W, Zhang Y, Li Y, Zhang M, Zhao L, Hu X, Wang S, Bao Z. (2018) FOXL2 and DMRT1L are Yin and Yang genes for determining timing of sex differentiation in the bivalve mollusk Patinopecten yessoensis. Frontiers in Physiology. 9: 1166.

Zhang M, Wang Y, Li Y, Li W, Li R, Xie X, Wang S, Hu X, Zhang L*, Bao Z. (2018) Identification and characterization of neuropeptides by transcriptome and proteome analyses in a bivalve mollusc Patinopecten yessoensis. Frontiers in Genetics. 9:197.

Li Y, Zhang L*, Sun Y, Ma X, Wang J, Li R, Zhang M, Wang S, Hu X, Bao Z. (2016) Transcriptome sequencing and comparative analysis of ovary and testis identifies potential key sex-related genes and pathways in scallop Patinopecten yessoensis. Marine Biotechnology. 18:453-465.

Xing Q, Li Y, Guo H, Yu Q, Huang X, Wang S, Hu X, Zhang L*, Bao Z. (2016) Cardiac performance: a thermal tolerance indicator in scallops. Marine Biology.163:244.

Wang S^#, Lv J^#, Zhang L^#, Dou J, Sun Y, Li X, Fu X, Dou H, Mao J, Hu X & Bao Z*. (2015) MethylRAD: a simple and scalable method for genome-wide DNA methylation profiling using methylation-dependent restriction enzymes. Open Biology. 5: 150130.

Fu X^#, Sun Y^#, Wang J, Xing Q, Zou J, Li R, Wang Z, Wang S, Hu X, Zhang L*, Bao Z*. (2014) Sequencing-based gene network analysis provides a core set of gene resource for understanding thermal adaptation in Zhikong scallop Chlamys farreri. Molecular Ecology Resources. 14: 184-198.

Zhang Y, Zhang R, Zou J, Hu X, Wang S, Zhang L*, Bao Z*. (2013) Identification and characterization of four ferritin subunits involved in immune defense of the Yesso scallop (Patinopecten yessoensis). Fish & Shellfish Immunology. 34: 1178-1187.

Zhang L, Hou R, Su H, Hu X, Wang S* & Bao Z*. (2012) Network analysis of oyster transcriptome revealed a cascade of cellular responses during recovery after heat shock.PLoS ONE. 7(4): e35484.