教育经历

1998-2002，中国海洋大学海洋生命学院，海洋生物技术与计算机科学双专业，学士

2002-2007，中国海洋大学海洋生命学院，遗传学专业，博士

2007-2009，美国德克萨斯大学奥斯汀分校整合生物系，博士后

2009-2010，美国德克萨斯大学奥斯汀分校神经生物系，博士后

工作经历

2020至今，中国海洋大学，方宗熙海洋生物进化与发育研究中心，PI

2011至今，中国海洋大学，海洋生命学院，先后聘任“英才”、“筑峰”教授

主要研究方向及成果

主要从事海洋贝类遗传和基因组学研究。本团队近年来致力于研发适用于非模式生物基因组学研究的新技术和新方法，通过解析软体动物基因组特征和发育进化调控机制等，从系统生物学角度理解贝类起源、重要性状发育调控和演化机制。已在国内外主流刊物发表论文上百余篇，成果发表在Nature Methods、Nature Ecology & Evolution、Nature Communications、Nature Protocols、Genome Research等国际权威期刊上。主持承担了国家863重大、国家重点研发计划等项目课题；入选国家高层次人才计划、国家基金委优青、山东省泰山学者特聘专家。成果入选2016、2017、2020年度中国海洋与湖沼十大科技进展及2017年度中国海洋科技十大进展。

主要学术奖项

教育部青年科学奖，中国动物学会青年科技奖，国家技术发明二等奖1项，省部级一等奖2项等。

代表性成果（#共同贡献；*通讯作者）

Note, for most recent publications, please visit:https://www.researchgate.net/profile/Shi_Wang3/

  1. Yu H#, Li Y#,*, Han W, Bao L, Liu F, Ma Y, Pu Z, Zeng Q, Zhang L, Bao Z, Wang S*. (2023) Pan-evolutionary and regulatory genome architecture delineated by integrated macro-and microsynteny approach. Nature Protocols. Accepted. 

2. Wei J^#, Liu P^#, Liu F^#, Jiang A, Qiao J, Pu Z, Wang B, Zhang J, Jia D, Li Y*, Wang S*, Dong B*. (2022) EDomics: a comprehensive and comparative multi-omics database for animal evo-devo. Nucleic Acids Research. 51(D1): D913-D923.

3. Han W^#, Liu L^#, Wang J^#, Wei H^#, Li Y^#, Zhang L^#, Guo Z, Li Y, Liu T, Zeng Q, Xing Q, Shu Y, Wang T, Yang Y, Zhang M, Li R, Yu J, Pu Z, Lv J, Lian S, Hu J, Hu X, Bao Z, Bao L^*, Zhang L^*, Wang S^*. (2022) Ancient homomorphy of molluscan sex chromosomes sustained by reversible sex-biased genes and sex determiner translocation. Nature Ecology & Evolution. 6: 1891-1906. 

4. Thimmappa R*, Wang S^#, Zheng M^#, Misra RC, Huang AC, Saalbach G, Chang Y, Zhou Z, Hinman V, Bao Z, Osbourn A*. (2022) Biosynthesis of saponin defensive compounds in sea cucumbers. Nature Chemical Biology. 18: 774-781.

5. Sun Z^#, Huang S^#,*, Zhu P, Tzehau L, Zhao H, Lv J, Zhang R, Zhou L, Niu Q, Wang X, Zhang M, Jing G, Bao Z, Liu J, Wang S^*, Xu J^*. (2022) Species-resolved sequencing of low-biomass or degraded microbiomes using 2bRAD-M. Genome Biology. 23: 36.

6. Liu F, Li Y^*, Yu H, Zhang L, Hu J, Bao Z, Wang S^*. (2021) MolluscDB: an integrated functional and evolutionary genomics database for the hyper-diverse animal phylum Mollusca. Nucleic Acids Research. 49: D988-D997.

7. Bao Y^#, Zeng Q^#, Wang J^#, Zhang Z^#, Zhang Y^#, Wang S^#, Wong N^#, Yuan W, Huang Y, Zhang W, Liu J, Lv L, Xue Q, Zha S, Peng Z, Yao H, Bao Z, Wang S^*, Lin Z^*. (2021) Genomic insights into the origin and evolution of molluscan red-bloodedness in the blood clam Tegillarca granosa. Molecular Biology and Evolution. 38: 2351-2365.

8. Wang J^#, Zhang L^#, Lian S^#, Qin Z^#, Zhu X^#, Dai X, Huang Z, Ke C, Zhou Z, Wei J, Liu P, Hu N, Zeng Q, Dong B, Dong Y, Kong D, Zhang Z, Liu S, Xia Y, Li Y, Zhao L, Xing Q, Huang X, Hu X, Bao Z, Wang S^*. (2020) Evolutionary transcriptomics of metazoan biphasic life cycle supports a single intercalation origin of metazoan larvae. Nature Ecology & Evolution. 4: 725-736.

9. Lv J^#, Jiao W^#, Guo H^#, Liu P, Wang R, Zhang L, Zeng Q, Hu X, Bao Z, Wang S^*. (2018) HD-Marker: a highly multiplexed and flexible approach for targeted genotyping of more than 10,000 genes in a single-tube assay. Genome Research. 28: 1919-1930.

10. Wang S^#, Zhang J^#, Jiao W^#, Li J^#, Xun X^#, Sun Y^#, Guo X^#, Huan P^#, Dong B, Zhang L, Hu X, Sun X, Wang J, Zhao C, Wang Y, Wang D, Huang X, Wang R, Lv J, Li Y, Zhang Z, Liu B, Lu W, Hui Y, Liang J, Zhou Z, Hou R, Li X, Liu Y, Li H, Ning X, Lin Y, Zhao L, Xing Q, Dou J, Li Y, Mao J, Guo H, Dou H, Li T, Mu C, Jiang W, Fu Q, Fu X, Miao Y, Liu J, Yu Q, Li R, Liao H, Li X, Kong Y, Jiang Z, Chourrout D^*, Li R^*, Bao Z^*. (2017) Scallop genome provides insights into evolution of bilaterian karyotype and development. Nature Ecology & Evolution. 1: 0120.

11. Li Y^#, Sun X^#, Hu X^#, Xun X^#, Zhang J^#, Guo X^#, Jiao W, Zhang L, Liu W, Wang J, Li J, Sun Y, Miao Y, Zhang X, Cheng T, Xu G, Fu X, Wang Y, Yu X, Huang X, Lu W, Lv J, Mu C, Wang D, Li X, Xia Y, Li Y, Yang Z, Wang F, Zhang L, Xing Q, Dou H, Ning X, Dou J, Li Y, Kong D, Liu Y, Jiang Z, Li R, Wang S^*, Bao Z^*. (2017) Scallop genome reveals molecular adaptations to semi-sessile life and neurotoxins. Nature Communications. 8: 1721.

12. Dou J^#, Dou H^#, Mu C, Zhang L, Zhou Z, Chang Y, Wang J, Li T, Li Y, Hu X, Wang S^*, Bao Z^*. (2017) Whole-genome restriction mapping by “subhaploid”-based RAD sequencing: an efficient and flexible approach for physical mapping and genome scaffolding. Genetics. 206: 1237-1250.

13. Wang S^#,*, Liu P^#, Lv J, Li Y, Cheng T, Zhang L, Xia Y, Sun H, Hu X, Bao Z^*. (2016) Serial sequencing of isolength RAD tags for cost-efficient genome-wide profiling of genetic and epigenetic variations. Nature Protocols. 11: 2189-2200.

14. Wang S^#,*, Meyer E^#,*, McKay JK, Matz MV. (2012) 2b-RAD: a simple and flexible method for genome-wide genotyping. Nature Methods. 9: 808-810.

15. Ponomarev I^*,#, Wang S^#, Zhang L, Harris RA & Mayfield RD^*. (2012) Gene co-expression networks in human brain identify epigenetic modifications in alcohol dependence. Journal of Neuroscience. 32: 1884-1897.

16. Wang S^*, Zhang L, Meyer E, Matz MV. (2009) Construction of a high-resolution genetic linkage map and comparative genome analysis for the reef-building coral Acropora millepora. Genome Biology.10: R126.