Guangxia Miao from University of California: Making and breaking cell-cell contacts in development
方宗熙-萨斯海洋分子生物学研究中心(Sars-Fang Centre)将邀请加利福尼亚大学苗光夏博士进行在线学术报告。报告详情:
苗光夏博士简介:
Assistant Project Scientist , Department of Molecular, Cellular, and Developmental Biology, University of California.
From 2012 to 2015, Guangxia Miao got his PhD degree in Biology, Kobe University, Kobe, Japan. Since 2016, he studied as a Postdoc Fellow/Assistant Project Scientist in Denise Montell lab, UC Santa Barbara, Santa Barbara, USA. He is engaged in assessing the Drosophila border cells as a model system to study how migratory cells establish stable connections with new partners at their destinations. He uncovered the contributions of gap-junction-forming innexin proteins and microtubules to this process.This work resulted in two publications in Developmental Cell and Star Protocol, and one publication is under revision.
代表性成果:
1. Miao, G.,* Guo, L., and Montell, D.J.* (2022). Collective polarity and migration of Drosophila border cells require Cactin, a spliceosome component. Journal of Cell Biology under revision.
2. Miao, G.*and Montell, D.J.* (2021). A thermo-genetics protocol for detecting gap junction channels in Drosophila egg chambers. Star Protocols 2, e100269
https://www.sciencedirect.com/science/article/pii/S2666166720302562?via%3Dihub
3. Miao, G., Godt, D., and Montell, D.J.* (2020). Integration of migratory cells into a new site in vivo. requires channel-independent functions of innexins on microtubules. Dev. Cell 54, 501-515.e9.
https://www.sciencedirect.com/science/article/pii/S1534580720305037
4. Liufu, Z., Zhao, Y., Guo, L., Miao, G., Xiao, J., Lyu, Y., Wu, C.-I.* (2017). Redundant and incoherent regulations of multiple phenotypes suggest microRNAs’ role in stability control. Genome Res. 27, 1665-1673.
https://genome.cshlp.org/content/27/10/1665.full
5. Miao, G. and Hayashi, S.*(2016). Escargot controls the sequential specification of two tracheal tip cell types by suppressing FGF signaling in Drosophila. Development 143, 4261–4271.
https://journals.biologists.com/dev/article/143/22/4261/47483/Escargot-controlsthe-sequential-specification-of
6. Miao, G. and Hayashi, S.* (2015). Manipulation of gene expression by infrared laser heat shock and its application to the study of tracheal development in Drosophila. Dev. Dyn. 244, 479–487.
https://anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.24192
7.Dong, B., Miao, G. and Hayashi, S.* (2014). A fat body-derived apical extracellularmatrix enzyme is transported to the tracheal lumen and is required for tube morphogenesis in Drosophila. Development 141, 4104–4109.
https://journals.biologists.com/dev/article/141/21/4104/46365/A-fat-bodyderived-apical-extracellular-matrix