教授 博士生导师

邮箱：shangao@ouc.edu.cn

电话：0532-82031935

地址：中国海洋大学鱼山校区达尔文馆211室

个人履历

  2011年获中国海洋大学理学博士学位，2006年10月-2007年3月作为中德交换生赴德国基尔大学学习，2009年1月-2010年12月作为联合培养博士生赴美国密歇根大学学习，2011年7月-2014年1月继续在美国密歇根大学病理学系做博士后工作，2014年受聘为中国海洋大学教授。国家优秀青年基金获得者，2021年获得国家杰出青年科学基金，现任中国原生动物学会理事。

研究方向/领域

  以嗜热四膜虫为模式生物，从事表观遗传学的研究，主要兴趣包括：1）DNA复制的表观遗传调控机制； 2）表观遗传信息对四膜虫大小核分化及基因表达的调控机理。  

代表性专著

1. Shan Gao, Ling Lu, Yan Bai, Weibo Song, and Cunming Duan. Structural and functional analysis of amphioxus HIFα reveals ancient features of the HIFα family. FASEB Journal, 2014, 28, 1880-1890 (IF=6.2).  

2. Feng Gao, Shan Gao (通讯作者), Pu Wang, Laura Katz, and Weibo Song. Phylogenetic analyses of cyclidiids (Protista,Ciliophora, Scuticociliatia) based on multiple genes suggest their close relationship with thigmotrichids. Molecular Phylogenetics and Evolution, 2014, 75, 219-226 (IF=4.2).  

3. Shan Gao, Jie Xiong, Chunchao Zhang, Brian R. Berquist, Rendong Yang, Meng Zhao, Anthony J. Molascon, Shaina Y. Kwiatkowski, Dongxia Yuan, Zhaohui Qin, Jianfen Wen, Geoffrey M. Kapler, Philip C. Andrews, Wei Miao, and Yifan Liu. Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & Development, 2013, 27, 1662-1679 (IF=12.6).  

4. Yuan Xu, Shan Gao (通讯作者), Xiaozhong Hu, Khaled AS Al-Rasheid, and Weibo Song. Phylogeny and systematic revision of the karyorelictid genus Remanella (Ciliophora, Karyorelictea) with descriptions of two new species. European Journal of Protistology, 2013, 49, 438-452 (IF=2.3).  

5. Jiamei Li, Weiwei Liu, and Shan Gao (通讯作者), Alan Warren, Weibo Song. Multigene-based analyses of the phylogenetic evolution of oligotrich ciliates, with consideration of the Internal Transcribed Spacer 2 secondary structure of  three systematically ambiguous genera. Eukaryotic Cell, 2013, 12, 430-437 (IF=3.7).  

6. Shan Gao and Yifan Liu. Intercepting noncoding messages between germline and soma. Genes & Development, 2012, 26,

 1774-1779 (IF=12.6).  

7. Shan Gao, Jie Huang, Jiamei Li, and and Weibo Song. Molecular phylogeny of the cyrtophorid ciliates (Protozoa,Ciliophora, Phyllopharyngea). Plos One, 2012, 7 (3), e33198 (IF=4.1).  

8. Shan Gao, Michaela C. Strüder-Kypke, Khaled A. S. Al-Rasheid, Xiaofeng Lin, and Weibo Song. Molecular phylogeny of three ambiguous ciliate genera: Kentrophoros, Trachelolophos and Trachelotractus (Alveolata, Ciliophora). Zoologica Scripta, 2010, 39, 305-313 (IF=3.1).  

9. Chunchao Zhang, Shan Gao, Yifan Liu, and Philip C. Andrews. Quantitative Proteomics Reveals Histone Modifications in Crosstalk with H3 Lysine 27 Methylation. Molecular & Cellular Proteomics, 2014, 13, 749-759 (IF=7.3).  

10. Chunchao Zhang, Anthony J. Molascon, Shan Gao, Yifan Liu, and Philip C. Andrews. Quantitative proteomics reveals that the specific methyltransferases Txr1p and Ezl2p differentially affect the mono-, di-and tri-methylation states of histone H3 lysine 27. Molecular & Cellular Proteomics, 2013, 12, 1678�1688 (IF=7.3).  

11. Xiangrui Chen, Shan Gao, Weiwei Liu, Weibo Song, Khaled AS Al-Rasheid, and Alan Warren. Taxonomic descriptions of three marine colepid ciliates, Nolandia sinica spec. nov., Apocoleps caoi spec. nov. and Tiarina fusa (Claparède & Lachmann, 1858) Bergh, 1881 (Ciliophora, Prorodontida). International journal of systematic and evolutionary microbiology, 2012, 62, 735-744 (IF=2.8).   

12. Xiangrui Chen, Shan Gao, Weibo Song, Khaled A. S. Al-Rasheid, Alan Warren, Jun Gong, and Xiaofeng Lin.Parabirojimia multinucleata spec. nov. and Anteholosticha scutellum (Cohn, 1866) Berger, 2003, two marine ciliates (Ciliophora, Hypotrichida) from tropical waters in southern China, with note on their SSU rRNA gene sequences. International Journal of Systematic and Evolutionary Microbiology, 2010, 60, 234-243 (IF=2.8).  

13. Cunming Duan, Hongxia Ren, and Shan Gao. Insulin-like growth factors (IGFs), IGF receptors, and IGF-bindingproteins: Roles in skeletal muscle growth and differentiation. General and Comparative Endocrinology, 2010, 167, 344-351 (IF=2.7).