李语丽 副教授 硕士生导师
Email: liyuli@ouc.edu.cn
地址：山东省青岛市市南区鱼山路5号中国海洋大学海洋生命学院
学习工作经历：
2022.09-至今 中国海洋大学海洋生命学院，“青年英才”工程第一层次，教授
2019.01-至今中国海洋大学海洋生命学院，“青年英才”工程第三层次，副教授
2015.09-2018.09中国海洋大学海洋生命学院，贝类基因组学，博士后
2012.09-2015.06 中国科学院北京基因组研究所，生物信息学专业，博士
2009.09-2012.06 中国科学院北京基因组研究所，基因组学专业，硕士
2005.09-2009.06 山东农业大学生命科学学院，生物工程专业，学士
研究方向：
主要从事贝类基因组学研究，聚焦在三个方面：1）贝类进化与适应的分子基础解析；2）贝类综合数据库的构建；3）组学技术的研发与利用。
主持项目：
1. 国家自然科学基金优秀青年基金：贝类基因组学（32222085），2023.01–2025.12，200万
2. 中国海洋大学优秀青年科技人才培育计划（A类），2023.01–2025.12，100万
3. 中国海洋大学优秀青年科技人才培育计划（B类），2021.01–2022.12，50万
4. 中国海洋大学“青年英才工程”科研启动经费，2019.06–2021.06，30万
5. 国家自然科学基金青年基金：扇贝闭壳肌“分子杂合”特征的遗传调控基础解析(31702330)，2018.01–2020.12，30万
Wei J#, Liu P#, Liu F#, Jiang A, Qiao J, Pu Z, Wang B, Zhang J, Jia D, Li Y*, Wang S*, Dong B*. EDomics: a comprehensive and comparative multi-omics database for animal evo-devo. Nucleic Acids Research, 2023, 51(D1): D913–D923.
Han W#, Liu L#, Wang J#, Wei H#, Li Y#, Zhang L#, Guo Z, Li Y, Liu T, Zeng Q, Xing Q, Shu Y, Wang T, Yang Y, Zhang M, Li R, Yu J, Pu Z, Lv J, Lian S, Hu J, Hu X, Bao Z, Bao L*, Zhang L*, Wang S*. (2022) Ancient homomorphy of molluscan sex chromosomes sustained by reversible sex-biased genes and sex determiner translocation. Nature Ecology & Evolution, 6(12):1891-1906. (Cover story)
Li Y#, Liu Y#, Yu H, Liu F, Han W, Zeng Q, Zhang Y, Zhang L, Hu J, Bao Z, & Wang S*. (2022). Adaptive bird-like genome miniaturization during the evolution of scallop swimming lifestyle. Genomics, Proteomics & Bioinformatics,20(6):1066-1077. (Cover story)
Liu F, Li Y*, Yu H, Zhang L, Hu J, Bao Z and Wang S*. MolluscDB: an integrated functional and evolutionary genomics database for the hyper-diverse animal phylum Mollusca. Nucleic Acids Research, 2021, 49(D1): D988-D997.
Wang J#, Yu H#, Yao L#, Li Y*, Liu F, Han W, Cui C, Hu J, Bao Z and Wang S*. Genomic and transcriptomic landscapes and evolutionary dynamics of molluscan glycoside hydrolase families with implications for algae-feeding biology. Computational and Structural Biotechnology Journal, 2020, 18: 2744-2756.
Li Y#, Sun X#, Hu X#, Jiao W#, Xun X#, Zhang J#, Guo X#, Zhang L, Liu W, Wang J, Li J, Sun Y, Miao Y, Cheng T, Xu GL, Fu X, Wang Y, Yu X, Huang X, Lu W, Lv J, Mu C, Wang D, Li X, Xia Y, Li YP, Yang Z, Wang F, Zhang L, Xing Q, Dou H, Ning X, Dou J, Li Y, Kong D, Liu Y, Jiang Z, Li R, Wang S* & Bao Z*, Scallop genome reveals molecular adaptations to semi-sessile life and neurotoxins, Nature Communications, 2017, 8:1721.
Li Y#, Wang R#, Xun X#, Wang J#, Bao L#, Thimmappa R#, Ding J#, Jiang J#, Zhang L, Li T, Lv J, Mu C, Hu X, Zhang L, Liu J, Li Y, Yao L, Jiao W, Wang Y, Lian S, Zhao Z, Zhan Y, Huang X, Liao H, Wang J, Sun H, Mi X, Xia Y, Xing Q, Lu W, Osbourn A, Zhou Z*, Chang Y*, Bao Z* & Wang S*. Sea cucumber genome provides insights into saponin biosynthesis and aestivation regulation, Cell Discovery, 2018, 4: 29.
Li Y#, Wang X#, Chen T#, Yao F, Li C, Tang Q, Sun M, Sun G, Hu S, Yu J, Song S*, RNA-Seq Based De Novo Transcriptome Assembly and Gene Discovery of Cistanche deserticola Fleshy Stem, Plos One, 2015, 10(5): e0125722.
Li Y#, Song S#,*, Wang X, Li C, Hu S, Yu J, Transcriptome-wide N(6)-methyladenosine profiling of rice callus and leaf reveals the presence of tissue-specific competitors involved in selective mRNA modification, RNA Biology, 2014, 11(9): 1180-1188.
Li Y, Song S*, Li C, Yu J, MeRIP-PF: an easy-to-use pipeline for high-resolution peak-finding in MeRIP-Seq data, Genomics Proteomics Bioinformatics, 2013, 11(1):72-75.
Wang S#, Zhang J#, Jiao W#, Li J#, Xun X#, Sun Y#, Guo X#, Huan P #, Dong B, Zhang L, Hu X, Sun X, Wang J, Zhao C, Wang Y, Wang D, Huang X, Wang R, Lv J, Li Y, Zhang Z, Liu B, Lu W, Hui Y, Liang J, Zhou Z, Hou R, Li X, Liu Y, Li H, Ning X, Lin Y, Zhao L, Xing Q, Dou J, Li YP, Mao J, Guo H, Dou H, Li T, Mu C, Jiang W, Fu Q, Fu X, Miao Y, Liu J, Yu Q, Li R, Liao H, Li X, Kong Y, Jiang Z, Chourrout D*, Li R* & Bao Z*, Scallop genome provides insights into evolution of bilaterian karyotype and development, Nature Ecology & Evolution, 2017, 1(5):120.
Dou J#, Dou H#, Mu C, Zhang L, Li Y, Wang J, Li T, Li Y, Hu X, Wang S*, Bao Z*, Whole-genome restriction mapping by “subhaploid”-based RAD sequencing: an efficient and flexible approach for physical mapping and genome scaffolding, Genetics, 2017, 206: 1237~1250.
Wang X#, Song S#,*, Wu Y#, Li Y, Chen T, Huang Z, Liu S, Dunwell T, Pfeifer G, Dunwell J, Wamaedeesa R, Ullah I, Wang Y, Hu S*, Genome-wide mapping of 5-hydroxymethylcytosine in three rice cultivars reveals its preferential localization in transcriptionally silent transposable element genes, Journal of Experimental Botany, 2015, 66(21): 6651-6663.