1992~1996，南开大学环境科学系，学士，环境生物专业

1996~2002，中国科学院海洋研究所，硕士/博士，海洋生物专业

2003~2009，中国科学院海洋研究所，副研究员

2011~ 2012-04, 日本神户大学 博士后

2014至今，中国海洋大学海洋生命学院，副教授

主要研究领域：

动物胚胎早期发育、器官发生与进化、动物地理学等研究

主要业绩：

主要从事海洋动物胚胎早期发育以及环境适应与演化等研究，作为负责人承担山东省自然科学基金“”海鞘重要器官细胞谱系构建及比较分析研究”。作为子课题负责人承担国家重点研发项目“外来水生生物对水域系统的影响及入侵风险评估和防控”课题四“入侵水生生物交互式数据库的构建与风险预警平台研发”以及国家重点研发项目“细胞外基质在管腔器官形态发生与稳态维持中的角色和功能研究”等。发表SCI论文30余篇，申请专利多项。

代表性成果：（#共同第一；*通讯作者）

1. Zhang, Jin ;Tan, Zicheng ;Qin, Qishu ;Peng, Hongzhe ;Shi, Wenjie ; Yu, Haiyan* ; Dong, Bo*. Integrated multi-omics identify key signalling pathways for notochord lumenogenesis in ascidian Ciona savignyi. Open Biology, 2025 ,15 (4)  DOI：10.1098/rsob.240402

2. He Muchun#, Li Yuting#, Li Yajuan, Dong Bo, Yu Haiyan*. Dynamics of Chromatin Opening across Larval Development in the Urochordate Ascidian Ciona savignyi. International Journal of Molecular Sciences. 2024, 25(5), 2793; https://doi.org/10.3390/ijms25052793

3. Zhang Wei, Jiang An, Yu Haiyan*, Dong Bo*. Comparative Transcriptomic Analysis Reveals the Functionally Segmented Intestine in Tunicate Ascidian. International Journal of Molecular Sciences, 2023, 24(7).

4. Ouyang Xiuke, Wu Bingtong, Yu Haiyan, Dong Bo*. DYRK1-mediated phosphorylation of endocytic components is required for extracellular lumen expansion in ascidian notochord. Biological Research 2023, 56(1).

5. Yang Yang, Yuting Zhu, Haiming Liu, Haiyan Yu *& Bo Dong *. Cultivation of gut microorganisms of the marine ascidian Halocynthiaroretzi reveals their potential roles in the environmental adaptation of their host. Mar Life Sci Technol 4, 201–207 (2022). https://doi.org/10.1007/s42995-022-00131-4

6. Zhuqing Wang, Xueping Sun, Xiaoming Zhang, Bo Dong & Haiyan Yu*. Development of a miRNA Sensor by an Inducible CRISPR-Cas9 Construct in Ciona Embryogenesis. Mol Biotechnol 63, 613–620 (2021). https://doi.org/10.1007/s12033-021-00324-9

7. Zhang Jin, Wei Jiankai, Yu Haiyan* & Dong Bo*. 2021. Genome-Wide Identification, Comparison, and Expression Analysis of Transcription Factors in Ascidian Styela clava. International Journal of Molecular Sciences22, no. 9: 4317. https://doi.org/10.3390/ijms22094317